白魔芋精粉对荷瘤小鼠的抑瘤和免疫增强作用

ANTITUMOR AND IMMUNOENHANCEMENT ACTIVITY OF AMORPHOPHALLUS ALBUS REFINED POWDER ON NEOPLASM BEARING MICE

方法：用２５、５０、１００ｍｇ／ｋｇ白魔芋精粉（ＡＡＰ）对Ｓ１８０、ＥＡＣ、Ｈｅｐｓ和Ｕ１４四瘤株进行了动物移植性肿瘤的抑瘤试验。结果：ＡＡＰ对Ｓ１８０、ＥＡＣ、Ｈｅｐｓ和Ｕ１４的抑瘤率分别为５９．７４％、５４．０２％、５２．７９％和４０．８６％。ＡＡＰ能显著增强荷瘤小鼠单核巨噬细胞的吞噬功能，与对照组相比，差异极显著（Ｐ＜０．０１），Ｔ淋巴细胞转化能力也显著高于对照组（Ｐ＜０．０１）。

The antitumor and immunoenhancement activity in neoplasm bearing mice of Amorphophallus albus,a refined powder(AAP)product from amorphophallus albus tuber was studied.The inhibitory rates of AAP(25mg/kg,ig)on S 180 ,EAC,Heps,U 14 were 57.94%, 54.02%, 52.22%, 40.86% respectively.Compared with the control,the phagocytic function of mononuclear macrophage and the T lymphocyte proliferation of EAC bearing mice treated with AAP were increased significantly(P<0.01).The tumor number and weight of concomitant tumor immunity test groups were decreased greatly(P<0.01).It suggested that AAP could augment cellullar immune action and inhibit tumor growth in neoplasm bearing mice.