摘要
卵黄免疫球蛋白(eggyolk immunoglobulin,IgY)是鸟类、两栖类和爬行类动物的主要免疫球蛋白。IgY稳定性好,具有不激活补体系统、不与类风湿因子和蛋白A、G结合等免疫学特性,且产量高、易提取纯化。该蛋白已广泛应用于兽医学、功能食品和生物制品等方面,且在疾病预防控制和治疗方面开发潜力广阔。本文就从IgY在生物学特性、提取、纯化,以及其在免疫诊断和免疫治疗方面的应用作一综述。
Egg yolk immunoglobulin（IgY） is a major immunoglobulin from birds,amphibians and reptiles.IgY does not activate mammalian complement system,and does not bind to mammalian rheumatoid factors,protein A or G.In addition,it has a high yield,and is easy to extract and purify.With these advantages,IgY has been widely used in veterinary science,functional food and bio-products,and proved potential application for disease control and treatment.This paper reviews biological characteristics of IgY,its extraction,purification, and application in immunodiagnosis and treatment.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
2009年第6期527-530,共4页
Chinese Journal of Parasitology and Parasitic Diseases
基金
国家科技支撑计划(No.2008BAI56B03)~~
关键词
卵黄免疫球蛋白
免疫
制备
诊断
治疗
Egg yolk immunoglobulin（IgY）
Immunization
Preparation
Diagnosis
Treatment
