角膜基质层烧烙联合羊膜移植治疗大泡性角膜病变

Treatment of bullous keratopathy by corneal stromal cauterization combined with amniotic membrane transplantation

目的探讨角膜基质层烧烙联合羊膜移植治疗大泡性角膜病变(BK)的临床疗效。方法对9例(9只眼)大泡性角膜病变的患者行角膜基质层烧烙联合羊膜移植,其中白内障联合人工晶状体植入术后5例,抗青光眼术后3例,角膜穿通伤1例。结果术后眼部刺激症状、角膜上皮大泡均于1周内消退,角膜基质水肿7～10d消失。术后随访3～24个月,均未发现BK复发及并发症的发生。结论对于症状明显、病情顽固、难以恢复有效视力且不具备角膜移植条件的BK患者,角膜基质层烧烙联合羊膜移植可有效控制BK的症状,防止BK的复发,是治疗BK可供选择的有效方法。

Objective To study the effects of corneal stromal cauterization combined amniotic membrana transplantation（AMT） in treating bullous keratopathy（BK）. Methods A total of 9 cases（9 eyes）,including 5cases intraocular lens implantation,3 cases absolute glaucoma and 1 case comeal penetration injury,were treated by corneal stromal cauterization combined with AMT .Results Irritate symtoms and corneal bullous were relieved in one week in all patients. Corneal edema disappear in 7~10 days. During the follow up period of 3~24 months,no complication or recurrence were found.Conclusion The methods of coeneal stromal cauterization combined with AMT is an effective treatment of bullous keratopathy with serious symptom,poor prognosis of visual acuity or unsuitable penetrating keratoplasty. It can effectively alleviate the symptom and prevent recurrence.