眼底自发荧光影像及其临床应用进展

Fundus autofluorescence and the progression of its clinical application

眼底自发荧光(FAF)影像是近二十年来开展的一项技术。它能够反映视网膜色素上皮(RPE)细胞的功能,也可以作为临床上RPE细胞代谢活力的一个指标。动态观察眼底自发荧光,可以监测病情的进展,判断疾病预后,结合进一步的基础实验研究,正确了解视网膜脉络膜病变的发病机制。本文就眼底自发荧光的原理,分布和检测方法及在临床应用的新进展作一综述。

Fundus autofluorescence is an imaging method developed in the last 20 years,which reflects the cellular function of retinal pigment epithelium （RPE） and the metabolism activity of RPE. It is quite helpful to monitor the progression and determine the prognosis of the chorioretinopathy by dynamic observation. Furthermore,it’s also helpful to study pathogenetic mechanism of some retina dieases. We review the basic theory of fundus autofluorescence and its clinical application in the various chorioretinopathy.