经皮腔内球囊瓣膜成形术治疗先天性肺动脉瓣狭窄的临床观察

Percutaneous transluminal balloon valvuloplasty of congenital pulmonary valve stenosis

目的：评价经皮腔内球囊瓣膜成形术（PTBV）对先天性肺动脉瓣狭窄（PS）患者的临床疗效及其安全性。方法：10例先天性PS患者住院接受PTBV术。结果：术后平均右室收缩压、平均跨动脉瓣压差、平均右室压与体循环收缩压比值均明显降低。平均随访4．5±2．8年，均存活。其中8例复查心脏B超，结果经肺动脉瓣最大流速和平均跨瓣压差也都明显下降。结论：PTBV术对先天性PS患者可显著且安全地解除其辩膜的狭窄，有效恢复或改善其血流动力学状况。

objective:To evaluate the curative effect and safety of percutaneous transluminal balloon valvuloplasty (PTBV) of congenital pulmonary valve stenosis (CPVS). Method: PTBV procedures were performed in 10 patients suffering from CPVS. Result:After PTBV the mean right ventricular systolic pressure,the mean transvalvular gradient and the mean right ventricular pressure expressed as a percent of systemic pressure decreased obviously. 10 patients were followed-up for mean 4. 5±2. 8 years,all of them were alive. Follow-up echocardiography revealed a significant change in the mean transvalvular gradient which decreased from 3. 92±1. 76 kPa to 2. 80±1. 50kPa (P <0. 05). Conclusion:PTBV is an effective and safe procedure in relieving pulmonary stenosis and improving the hemodynamic situation sequently.