中西医结合治疗慢性肾炎41例疗效观察

Observation of the curative effect in the treatment of 41 chronic nephritis cases by traditional Chinese and Western medicines

目的通过中西医结合的治疗方法,探讨黄芪与丹参注射液在治疗慢性肾炎中的疗效。方法将住院治疗的慢性肾炎患者79例,随机分为观察组41例和对照组38例。对照组采用常规对症治疗,观察组在对照组治疗基础上加用黄芪注射液与丹参注射液静脉滴注,观察2组病例的尿蛋白、血浆白蛋白、肾功能(BUN、Scr)的变化。结果观察组的尿蛋白与血浆白蛋白的变化与对照组比较有明显改善(P<0.01);观察组总有效率87.80%显著高于对照组的65.79%,差异有统计学意义(P<0.01)。结论黄芪与丹参注射液治疗慢性肾炎有其独特的理论基础和实用价值,对减少蛋白尿的发生、提高血浆白蛋白、改善肾脏功能,具有较好的疗效,且无不良反应,临床使用安全。

Objective Through the integrated therapy of traditional Chinese and Western medicines,search the curative effect of radix astragali combined salvia miltrorrhiza injection in the treatment of chronic nephritis. Methods Randomly divide 79 patients with chronic nephritis into the observation group including 41 patients and the control group including 38 patients,the control group treated with conventional Western medicine, the observation group was added based on the treatment of radix astragali and salvia miltrorrhiza injection by intravenous drip,observed the changes in urokinase protein,plasma albumin and nephros function （ BUN, Scr） of the two groups. Results Compared with that of the control group,the changes in urokinase protein and plasma albumin of the observation group improve remarkably（P 〈0.01 ）. The rate of total effective in observation group was significantly higher than control group （ 87. 80% vs 65. 79% ） , the difference was statistically significant （ P 〈 0. 01 ）. Conclusion There is unique theoretical basis and utility value for the treatment of chronic nephritis by radix astragali and salvia mihroIThiza injection,it has good curative effect on reducing the occurrence of urokinase protein, improving plasma albumin and improving nephros function,without any toxic side effect,the clinical use is safe.