摘要
从翼核果的茎中分离得到两个微量新化合物,分别为1,6二羟基3甲基口山酮8羧基1OβD吡喃葡萄糖苷(Ⅰ)及1,6二羟基3甲基口山酮8羧基1OβD吡喃葡萄糖基(1→6)βD吡喃葡萄糖苷(Ⅱ);命名为翼核口山酮苷及翼核口山酮二糖苷.测定了这两个化合物对人慢性髓样白血病细胞K562的抑制生长作用.
Two new minor compounds,1,6 dihydroxy 3 methyl xanthone 8 acid 1 O β D glycoside(Ⅰ)and 1,6 dihydroxy 3 methyl xanthone 8 acid 1 O β D glycosyl(1→6) β D glycoside(Ⅱ)were isolated from Ventilago leiocarpa Benth.These compounds were identified by UV,IR, 1H NMR, 13 C NMR,MS,HMBC,C H COSY and DEPT.They are named as ventilagoxanthonoside and ventilagoxanthobinoside.Pharmacological studies showed that compound(Ⅰ)and(Ⅱ)had inhibitive effects on the growth of K 562 cells.
出处
《沈阳药科大学学报》
CAS
CSCD
1998年第4期250-253,共4页
Journal of Shenyang Pharmaceutical University
基金
国家自然科学基金