硫酸乙酐法制备氟嗪酸中间体

Sulfuric Acid and Acetic Anhydride as a Cyclizing Agent for Preparation of Ofloxacin Intermediate

用硫酸乙酐混合物作环合剂，制备了氟嗪酸中间体．该方法具有反应条件温和、价格便宜、后处理简单的优点。

Sulfuric acid and acetic anhydride were used as a cyclizing agent to prepare Ofloxacin intermediate.The reaction could be carried out under moderate conditions and facilitate industrial produce.