奥扎格雷钠治疗急性脑梗死临床观察及其预后分析

Ozagrel clinical observation of the treatment of acute cerebral infarction and its prognosis analysis

目的:探讨奥扎格雷钠治疗急性脑梗死临床疗效及其对预后的影响。方法:对收治的急性脑梗死80例按入院时间随机分为实验组和对照组各40例,实验组采用奥扎格雷钠治疗,对照组采用复方丹参针治疗,疗程均2周,同时合理控制血压,降低颅压及其合并症和有关并发症的处理。治疗前后均行纤维蛋白原浓度、血粘度等实验室检查,观察临床疗效并随访3月。结果:实验组疗效明显优于对照组(P<0.05),实验组3月内发生TIA或脑梗死也少于对照组,有显著性差异(P<0.05)。结论:奥扎格雷钠能有效治疗急性脑梗死,并能有效改善其预后。

Objective To investigate the treatment of acute cerebral infarction Ozagrel clinical efficacy and its impact on prognosis. Methods To treat 80 cases of acute cerebral infarction according to admission time were randomly divided into experimental and control groups of the 40 cases, Ozagrel experimental treatment group, the control group used the needle Danshen treatment regimens two weeks, while the reasonable control of blood pressure, reduce the intracranial pressure and its complications and related complications. Line before and after treatment the concentration of fibrinogen, blood viscosity, such as laboratory tests, and follow - up observation of clinical efficacy in March. Results Efficacy of the experimental group wassuperior to the control group （ P 〈 0. 05 ）, the experimental group occurred in March also TIA or cerebral infarction is less than the control group, the difference wassignificant （ P 〈 0. 05 ）. Conclusions Ozagrel effective in the treatment of acute cerebral infarction, and can effectively improve their nroznosis.