儿科门急诊抗菌药物分线使用的调查

Antibacterial Use by Line Category in Pediatric Outpatient and Emergency Departmeats of a Hospital:A Survey

目的了解儿科门急诊抗菌药物临床分线使用情况。方法利用药物金额排序法，用药频度排序法的分析方法，对某院2008年7月1日～12月31日38998张儿科门急诊处方抗菌药物分线使用情况进行调查与分析。结果抗菌药物：一线用药DDDs占37．4％，金额占24．7％，二线用药DDDs占48．7％，金额占40．8％，三线用药DDDs占13．9％，金额占35．0％；金额排序前3位是头孢美唑钠粉针、阿奇霉素粉针、头孢呋辛钠粉针，用药频度排序前3位是头孢丙烯干混悬剂、阿奇霉素粉针、阿莫西林钠／克拉维酸钠粉针。结论各线药物中三线抗菌药物使用频率偏高，临床医师越级使用较普遍，应采取有效措施，加强抗菌药物使用管理。

OBJECTIVE To know the clinical antibacterial use by line category in pediatric outpatients and emergency departments. METHODS The antibacterial use by line category from the 38998 prescriptions of pediatric outpatient and emergency departments of a hospital from Jul 1st to Dec 31st 2008 according to the medicament amount and frequency were surveyed and analyzed. RESULTS First-line antibacterial drug DDDs accounted for 37.4% and 24.7% of the total amount; second-line drug DDDs accounted for 48.7V0 and 40.8% of the total amount and the third-line drug DDDs accounted for 13.9% and 35.0% of the total amount. The top three by total amount were cefmetazole sodium injection, azithromycin sodium injection and Cefuroxime sodium injection. According to the sorting method of DDDs, the top three were cefprozil dry suspension, azithromycin sodium injection and amoxicillin sodium clavulanate potassium injection. CONCLUSIONS Frequency of the third- line antibacterial drug using is relatively high. Clinicians have a tendency to skip a line category in using drugs. Effective measures should be taken to strengthen the management of antibacterials.