白癜风患者治疗前后血液流变学的改变及临床意义

Hemorheological changes and its meaning in vitiligo patients before and after treatment

目的:探讨白癜风治疗前后血液流变学的改变及临床意义。方法:对30例正常对照组及58例白癜风患者用白癜风颗粒剂、白癜风搽剂联合长波紫外线(UVA)光疗治疗前后进行血液流变学检测。结果:治疗总有效率达74.14%,治疗组治疗前血液流变学多项指标高于正常对照组(P<0.05),治疗后各项指标均下降(P<0.05)。结论:白癜风的发生与血液流变学的改变有关,白癜风颗粒剂、白癜风搽剂联合UVA光疗可通过改善血液流变学发挥疗效。

Objective： To observe the hemorheological change of vitiligo patients both before and after treatment by Vitiligo Granules or Vitiligo Liniment combined with UVA phototherapy, researching the relationship and clinical significance between vitiligo and hemorheology. Methods： Hemorheological detection was made before and after treatment for 30 normal cases and 58 cases of vitiligo. Res,ults： The total effective rate was 74.15%. The indexes levels of hemorheology of treatment group was higher than those of normal group before treatment （P 〈 0.05）, and decreased after treatment （P 〈 0.05）. Conlusion： The occnrence of vitiligo was related to the change of hemorheology. Vitiligo Granules or Vitiligo Liniment combined with UVA phototherapy could treat vitiligo by improving hemorheology.