摘要
目的:调查国内多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)患者胃肠功能损伤的流行病学情况。方法:采用多中心、前瞻性调查方法,分析2002年3月—2005年1月全国11省市的37家三级医院1087例MODS患者的病历资料。结果:1087例患者中,胃肠功能损伤的发生率、病死率分别为78.8%、61.7%。其中入住重症监护室(ICU)患者其28d病死率为58.9%。MODS患者胃肠功能损伤发生及死亡的高危因素分别为存在腹水、未应用或未适当应用肠内营养,用用肾上腺素等。结论:MODS患者胃肠功能损伤发生率高,其发生高危因素及死亡高危因素与腹水、肠内营养的应用等相关。患有胃肠功能损伤的MODS患者其入住ICU28d病死率较非胃肠功能损伤患者显著升高。
Objective:To investigate the epidemiology of gastrointestinal dysfunction in the patients with multiple organ dys function syndrome (MODS) in China. Methods: Prospectively collected data of 1 087 MODS patients between March 2002 and January 2005 were analysed. Patients were recruited from 37 tertiary hospitals of l 1 provinces in China. Results: The incidence and the mortality of gastrointestinal dysfunction in the MODS patients were 78. 8% and 61. 7%, repectively. The mortality within 28 days of ICU hospitalization was 58.9%. The risk factors of occurance and death included aseites, no proper intesinal nutrition, the use of epinephrine. Conclusions: MODS patients had high incidence rate of gastrointestinal dysfunction. And the MODS patients with gastrointestinal dysfunction had higher 28-day hospitalization motality than patients without it.
出处
《中国临床医学》
2009年第6期863-864,共2页
Chinese Journal of Clinical Medicine
基金
北京市科委科技计划重大项目(编号H020920050530)
关键词
多器官功能障碍综合征
胃肠功能损伤
流行病学
Multiple organ dysfunction syndrome
Gastrointestinal dysfunction
Epidemiology