阴道镜下宫颈活检的应用价值评价

Loop Electrosurgical Excision Procedure Evaluate the Clinical Value of Colposcopic Cervical Biopsies

目的:探讨阴道镜下宫颈活检的临床价值。方法:2005年9月—2008年9月,256例经阴道镜下宫颈活检并实施高频电波刀电圈切除术(LEEP术),其中上皮内瘤变(CIN)186例,宫颈炎70例,所有标本送病理检查,比较分析LEEP术前、后病理诊断及相关因素。结果:以宫颈锥切诊断为准,则阴道镜检查诊断宫颈疾病符合率为88.3%(226/256),其中宫颈炎97.1%(68/70),宫颈CIN分级诊断符合率准确性56.5%(105/186)。以锥切前后复核病理诊断为准,则阴道镜检查诊断宫颈疾病的准确率为97%,诊断宫颈癌及其CIN的准确性为87.1%(162/186)。结论:阴道镜下宫颈多点活检早期诊断宫颈癌及CIN具有极高的准确性,是宫颈癌三阶梯筛查的关键步骤,宜在临床广泛推广使用。

Objective：To asses the clinical value of colposcopic cervical biopsies. Methods： A retrospective analysis was carried out in 256 cases of cervical intraepithelial neoplasia （CIN）（ 186 cases） and eervicitis （70 cases） undergoing colposcopic cervical biopsies Loop electrosurgical excision procedure between September 2005 and September 2008,all the specimens undergoing pathology. Compare the pathologic diagnosis and relative factors of colposcopic cervical biopsies and t.eep. Results： The cornincidence rate of multiple biopsies before the procedures comparing with the conization ones was 88.3 % （226/256）, eervicitis 97. 1% （68/70）, CIN56.5% （105/186）. Conclusion： Colposcopic cervica multiple biopsies have high coincidence rate to diagnose CIN and cervical carcinoma,that is the key step for diagnosing cervical carcinoma . It can be widely used in clinic.