尿转铁蛋白在糖尿病肾病早期诊断中的价值

Determination of urinary transferrin and its application in diagnosis of diabetic nephropathy in early stage

采用激光免疫比浊法测定７５例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）病人尿转铁蛋白排泄率（ＵＴＥＲ）。结果表明：临床蛋白尿组及微量白蛋白尿组ＵＴＥＲ升高率分别为１００％、９６２％，而在尿白蛋白正常组，ＵＴＥＲ升高率仍可达２５０％，与尿白蛋白排泄率（ＵＡＥＲ）升高率比较，差异有非常显著意义（χ２＝７１，Ｐ＜００１）。

Laser-immune-nephelometry was used to determine urinary transferrin excretion rate (UTER) in 75 patients with non-insulin dependent diabetes mellifus (NIDDM) It was shown that the ratios of increased UTER in the group with clinical proteinuria and the group with minimal albuminuria were 100% and 962%, respectively Even in the group with normal urinary albumin excretion the positive rate of elevated UTER was 250%, which was significantly higher than the ratio of increased urinary albumin excretion rate (UAER) (χ2=812, P<001) It is concluded that the UTER is a sensitive index in diagnosis of diabetic nephropathy in early stage