急性心肌梗塞患者外周血IL-2、sIL-2R水平及动态变化的研究

Study of Changes of the Levels of Serum IL-2,sIL-2R in Patients with Acute Myocardial Infarction

本文测定了30例急性心肌梗塞患者外周血白细胞介素2（IL-2）及其游离受体（sIL-2R）水平，并进行动态观察，实验结果表明，发病后48h内IL-2水平最低，而sIL-2R水平最高，与正常对照组比较有显著性差异（P＜0.001）；发病后72hIL-2水平开始升高，sIL-2R水平开始下降，至2～3周时两者水平逐渐趋于正常，与对照组比较无显著性差异（P＞0．05）。研究表明急性心肌梗塞与机体免疫应答密切相关。

The levels of serum interleukin - 2 (IL - 2) and soluble interleukin - 2 recepter (sIL - 2R) of 30 Patients with acute myocardial infarction (AMI) was studied and their developments Observed. The results showed that,the level of IL- 2 is lowest on the second day after attack in AMI group, while the level of sIL - 2R is the highest (P<0. 001 ). The level of IL-2 began to increase and sIL -2R level have began to decrease from the 3rd day after AMI. Both IL - 2 level and sIL - 2R level have no prominant difference between AMI Patients and the control groups from the 14th day to the 21th day after AMI (P >0.05). Our conclusion confirms that AMI is closely related to the immunoreaction system.