性激素受体和基因蛋白在乳腺癌中表达的研究

RESEARCH ON THE EXPRESSION SEX HORMONE RECEPTOR AND GENE PROTEIN IN THEBREAST CANCER

收集乳腺癌手术切除标本73例,采用酶联组织化学方法,检测ER、PR。结果表明阳性率分别为78.08％、60.27％。利用免疫组织化学方法检测Bcl-2和c-fos基因蛋白,结果表明阳性率分别为79.25％和56.92％。对它们表达的意义进行讨论。

73 cases of breast cancer were collected. Estrogen receptor(ER)and progesterone receptor(PR) were examined with affinoperoxidasehistochemical method. At the same time Bel - 2 and C - fos gene protein werede-termined with immunohistochemistry method. The results showed thatthe positive rates of ER and PR were 78.08% and 60. 27% respectively, and the positive rates of Bcl - 2 and C - fos were 79. 25% and 56. 92%seperately. The significance of their expressions was discussed.