摘要
目的探讨老年肺炎合并慢性心功能不全患者凝血功能的改变。方法对我院急诊57例老年肺炎合并心衰患者进行BNP、APTT、PT、Fg、D-Dimer、CRP监测,并根据预后,将患者分为存活组/死亡组,分别观察患者的凝血功能的改变,凝血与感染的炎性指标CRP、BNP的关系,观察患者在肺部感染同时合并慢性心功能不全时凝血功能与预后的关系。结果研究发现老年肺炎合并慢性心功能不全患者均存在一定程度的凝血异常,表现为Fg、D-Dimer的升高和APTT、PT的延长。APTT、Fg、D-Dimer的变化与心衰严重程度和CRP有一定的相关,APTT、D-Dimer与预后相关,APTT和D-Dimer升高水平是影响肺炎合并慢性心力衰竭患者预后的独立危险因素。结论为临床通过一些干预手段来影响肺炎合并心衰患者的凝血功能,从而达到改善预后、降低死亡率提供一定的依据。
Objective To investigate the elderly pneumonia associated with blood coagulation in patients with chronic heart failure functional changes. Methods From 57 patients with senile pneumonia complicated by acute heart failure patients with BNP, APTT, PT, Fg, D-Dimer, CRP monitoring, and in accordance with the prognosis, patients were divided into the survival group / death group, were observed in patients with coagulation changes in indicators of coagulation and infection in inflammatory CRP, BNP relationship between the observed concomitant pulmonary infection in patients with chronic heart failure when the coagulation function and prognosis.Results elderly pneumonia associated with chronic heart failure patients had some degree of blood clotting abnormalities, expressed as Fg, D-Dimer levels and the APTT, PT extension. APTT, Fg, D-Dimer changes and heart failure severity and CRP related to a certain extent, APTT, D-Dimer and prognosis, APTT, and D-Dimer level was elevated pneumonia, the prognosis of patients with chronic heart failure independent risk factor. Conclusions for clinical interventions to influence through a number of pneumonia complicated by heart failure in patients with coagulation function, so as to achieve and improve prognosis and reduce mortality, provide some basis.
出处
《湖南中医药大学学报》
CAS
2009年第9期60-63,共4页
Journal of Hunan University of Chinese Medicine
