期刊文献+

低分子肝素——依诺肝素在经皮冠状动脉介入治疗围手术期的应用

The application of low molecular weight heparin-enoxaparin in percutaneous coronary intervention
下载PDF
导出
摘要 因肝素在用于经皮冠状动脉介入治疗的抗凝时,手术中难以监测性和可能的致血小板减少症等问题,引起了医生的顾虑。近年来,低分子肝素在这类手术中的抗凝方案已成为一个研究热点,本文综合相关文献,介绍了低分子肝素在经皮冠脉介入治疗中的使用相关问题。 Many problems such as inconvenient monitoring and heparin-induced thrombocytopenia occur in percutaneous coronary intervention when heparin is used for anticoagulation. Recently anticoagulation regimen using low molecular weight heparin in percutaneous coronary intervention has become the hot point of research. Some related literature are reviewed to introduce the application of low molecular weight heparin in percutaneous coronary intervention in this article.
出处 《药学服务与研究》 CAS CSCD 2009年第6期448-451,共4页 Pharmaceutical Care and Research
关键词 肝素 低分子量 依诺肝素 经皮冠状动脉介入治疗 综述 heparin,low molecular-weight enoxaparin percutaneous coronary intervention review
  • 相关文献

参考文献20

  • 1Cohen M, Theroux P, Borzak S, et al. Randomized doubleblind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and aspirin: tile ACUTE Ⅱ study. The Antithrombotic Combination Using Tirofiban and Enoxaparin[J]. Am Heart J,2002,144(3) : 470-477.
  • 2Goodman S G, Fitehett D, Armstrong F W,et al. Randomized evaluation of the safety and efficacy of enoxaparin versus unfractionated heparin in high-risk patients with non-ST-seg ment elevation acute coronary syndromes receiving the glycoprotein Ⅱ b/Ⅲ a inhibitor eptifibatide[J]. Circulation, 2003, 107(2) : 238-244.
  • 3Blazing M A,de Lemos J A,White H D,etal. Safety and efficacy of enoxaparin vs unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who reeeive tirofiban and aspirin:a randomized controlled trial[J]. JAMA,2004,292(1) :55-64.
  • 4Ferguson J J, Calif R M,Antman E M,et al. Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-seg ment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNER- GY randomized trial[J]. JAMA,2004,292(1) :45-54.
  • 5Antman E M, Morrow D A, McCabe C H, et al. Enoxaparin versus unfractionated heparin with fibrinolysis for ST-eleva tion myocardial infarction[J]. N Engl J Med, 2006,354 (14) :1477-1488.
  • 6Morrow D A, Wallentin L. Enoxaparin versus unfractionated heparin for STEMI: one year results of ExTRACT-TIMI 25 trial[EB/OL]. Program and abstracts of the European Society of Cardiology 2007 World Congress,Vienna, Austria.[2007- 09-06]. http://www, escardio, org/knowledge/congresses/ Congress-Reports/2007/hl-ctu/? hit=quick2007.
  • 7Gibson C M, Murphy S A, Montalescot G,et al. Percutaneous coronary intervention in patients receiving enoxaparin or un- fractionated heparin after fibrinolytic therapy for ST-segment elevation myocardial infarction in the ExTRACT-TIMI 25 trial[J]. J Am Coll Cardiol, 2007,49 (23) : 2238-2246.
  • 8Murphy S A, Gibson C M, Morrow D A,et al. Efficacy and safety of the low-molecular weight heparin enoxaparin compared with unfractionated heparin across the acute coronary syndrome spectrum: a meta-analysis[J]. Eur Heart J, 2007, 28(17) : 2077-2086.
  • 9White H D,Gallo R,Cohen M,et al. The use of intravenous enoxaparin in elective pereutaneous coronary intervention in patients with renal impairment: results from the safety and efficacy of enoxaparin in PCI patients, an international randomized evaluation (STEEPLE) trial[J]. Am Heart J,2009, 157(1) :125-131.
  • 10Tricoei P, Lokhnygina Y, Berdan L G.et al. Time to coronary angiography and outcomes among patients with high risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial [J]. Circulation. 2007. 116 (23) : 2669- 2677.

二级参考文献3

共引文献545

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部