老年原发性高血压患者凌晨血压增高与左心室肥厚的关系

Relationship between morning blood pressure surge and left ventricular hypertrophy in elderly essential hypertension

目的探讨老年原发性高血压患者凌晨血压增高(morning blood pressure,MBPS)与左心室肥厚的关系。方法采用动态血压监测仪分析62例老年原发性高血压患者凌晨血压的特点,根据MBPS差值,将凌晨血压增高≥23.6mmHg判断为凌晨血压增高(MBPS组,n=30),凌晨血压增高<23.6mmHg判断为非凌晨血压增高(NMBPS组,n=32),分别进行超声心动图检查,观察两组左心室质量指数(Left ventricular mass index,LVMI)。结果MBPS组LV-MI明显高于NMBPS组(P<0.01),且其凌晨收缩压、凌晨舒张压、凌晨脉压均明显高于NMBPS组(P<0.01)。结论老年原发性高血压患者凌晨血压增高促进了左心室肥厚的发展。

Objective To investigate the relationship between morning blood pressure surge （MBPS） and left ventricular hypertrophy in elderly essential hypertension patients. Method With ambulatory blood pressure monitoring, the characteristics of morning blood pressure in 62 elderly patients with hypertension were analyzed. MBPS was greater than or equal to 23.6mmHg judged for morning blood pressure surge, which were named MBPS group （30 cases） and the others were allocated into NMBPS group （22 cases）. The echoeardiography of the patients was measured and the left ventricular mass index （LVMI） was observed. Result The LVMI of MBPS group was significantly higher than that of NMBPS group（P〈0. 01）, and morning systolic blood pressure, diastolic blood pressure, pulse pressure in patients with MBPS group were higher than that in those NMBPS group（P〈0. 01）. Conclusion Morning blood pressure surge is closely related to the development of left ventricular hypertrophy in elderly patients with essential hypertension.