琥珀酰明胶注射液在冠脉介入治疗围手术期的应用

Application of gelofusine on coronary intervention

目的探讨琥珀酰明胶注射液在冠脉介入治疗术后应用的有效性和安全性。方法纳入40例接受冠脉支架植入术后患者,随机分为琥珀酰明胶注射液治疗组和常规治疗组,比较琥珀酰明胶注射液输注对于冠脉介入治疗患者术后血流动力学指标和肾功能的影响。结果琥珀酰明胶注射液治疗组术后血流动力学指标优于常规治疗组,高迷走反应发生率有下降的趋势。两组相比,琥珀酰明胶注射液治疗组血肌酐与对照组相比无显著差异。结论琥珀酰明胶注射液可以安全应用与冠脉介入治疗术后患者进行容量治疗,对于稳定血流动力学可能有利,其疗效可通过更大规模临床研究进一步证实。

Objective To investigate the effectiveness and safety of gelofusine injection on peri-operation period af- ter coronary intervention. Methods 40 cases treated with coronary stents were randomly divided into gelofusine injection treatment group and conventional treatment group. The hemodynamic and renal function were observed after coronary intervention. Results The parameters of hemodynamics after operation of gelofusine injection treatment group were superi- or to that of conventional treatment group. There was a low trend of incidence of vagal reactions in gelofusine injection treatment group, compared with that of conventional treatment group. There was no significant difference in serum creatinine of the two groups. Conclusion It is safe to apply gelofusine on patients after coronary intervention, which may be beneficial for the stability of hemodynamics of patients after coronary intervention.