双频复合超声提取中药有效成分的动力学数学模型研究

Mathematical kinetic model of dual-frequency ultrasound assisted extraction of effective components traditional Chinese medicine

目的:建立双频复合超声提取丹参有效成分的动力学数学模型。方法:在超声条件下的中药提取过程,当超声作用强度足够大时,扩散边界层可以无限小,以至溶质一经药材表面便迅速进入溶液主体中,可以假定整个提取过程由内扩散控制。根据Fick第二定律建立了丹参药材中的丹参酮类化合物双频复合超声强化溶剂提取过程的动力学模型。针对丹参药材颗粒大小、提取固液比对双频复合超声提取过程影响较大的因素进行了验证。结果:通过Origin软件进行数学模拟,得出拟合图形与实验值比较吻合。结论:双频复合超声条件下的丹参中药材提取过程是符合普通的提取动力学的。

Objective： To establish the mathematical kinetic model of the components extracted from the Salvia miltiorrhiza . Method： In the conditions of ultrasound extracting the course of traditional Chinese medicine, the role of ultrasound intensity is large enough, the proliferation of boundary layer can be infinitesimal, as well as the solute upon the surface of medicine quickly into the main solution,we can assume that the whole process of extraction from the control of proliferation. A mathematical model of dual-frequency ultrasound extraction kinetics based on Fick＇ s second diffusion law was established for traditional Chinese medicine. Based on material size and solid/liquid ratio significant factors. Result： We adopt Origin software to carry out a mathematics simulation, the result showed ：simulation graphics and experiment value are very fitting. Conclusion： This proves that S. miltiorrhiza extraction course accords with ordinary extraction dynamics equation at the dual-frequency ultrasound.