石南藤中木脂素和新木脂素成分的研究

Neolignans and lignan from Piper wallichii

目的:对石南藤的化学成分进行研究。方法:采用各种色谱技术进行分离纯化,并利用理化常数和波谱数据鉴定化合物结构。结果:从石南藤50%乙醇提取物的二氯甲烷萃取部位分离并鉴定了9个化合物,其中包括1个木脂素(-)-gal-belgin(1)和8个新木脂素:玉兰脂B(2),山蒟素D(3),(+)-licarin A(4),海风藤酮(5),南藤素(6),山蒟素C(7),山蒟素B(8),(+)-burchellin(9)。结论:化合物1,3,4,8,9为首次从该植物中分离得到。

To investigate the chemical constituents of the aerial part of Piper wallichii. Nine compounds were isolated by various chromatographic techniques and the structures were elucidated by their physicochemical properties and the spectral data analysis. Nine compounds were identified as one lignan （-）-galbelgin （1） and eight neolignans： denudatin B （2）, hancinone D （3）, （＋）-licarin A （4）, kadsurenone （5）, wallichinine （6）, hancinone C （7）, hancinone B （8）, （＋）-burchellin （9）. Compounds 1, 3, 4, 8, 9 were isolated from this plant for the first time.