正交试验优选阿胶、龟甲胶、鹿角胶的微波炮制胶珠工艺的研究

Orthogonal optimization of plastic beads microwave processing of Colla Corii Asini,Colla Carapacis et Plastri Testudinis,and Colla Cornus Cervi

目的优选微波炮制阿胶、龟甲胶、鹿角胶胶珠的工艺参数,规范胶类药材制珠工艺,提高并稳定胶珠质量。方法用多项指标评价胶珠质量,采用L4(23)正交优选法对炮制胶珠工艺参数进行筛选。结果获得了阿胶、龟甲胶、鹿角胶优化的炮制胶珠工艺参数。结论不同种类的胶材或不同批号、不同生产厂家的同类胶材都有其最适的工艺参数,可用正交试验优选法快速筛选。

Objective Colla Corii Asini , Colla Carapacis et Plastri Testudinis , Colla Comus Cervi , three types of plastic bead microwave process parameters were optimized in order to standardize the production of the types of plastic beads and to enhance the stability of the quatity of plastic beads. Methods Using a number of quality indicators to evaluate the quality of plastic beads and orthogonal test to optimize the plastic bead process parameters. Results The microwave process parameters of Colla Corii Asini, Colla Carapacis et Plastri Testudinis, Colla Comus Cervi, three types of plastic beads were obtained through orthogonal optimization. Conclusion Different types of plastic type drugs, different production lot, and different manufacturers of similar plastic herbs have their own optimum process parameters. L4 （2^3） orthogonal optimization can be used to screen out the plastic type drugs rapidly.