冠心病患者院内启动调脂治疗的临床研究

In-hospital Initiation of Lipid-lowering Therapy for Patients with Coronary Heart Disease

目的:探讨冠心病(CHD)患者院内启动调脂治疗对服药依从性和临床预后的影响。方法:398例住院CHD患者,采用回顾性资料分析和门诊及电话随访方法。结果:CHD患者出院前服用调脂药物占75.9%,应接受调脂治疗的患者平均随访17个月后,院内启动调脂治疗组服用调脂药物比例明显高于院内未启动调脂治疗组(P<0.01),出院后至少进行一次血脂复查者比例院内启动调脂治疗组同样高于未启动调脂治疗组(P<0.05),LDL-C达标率两组间没有显著性差别,两组间心血管事件发生率未见统计学差异(P均>0.05)。结论:院内启动调脂治疗可改善患者依从性,提高服药率。

Objective ：To investigate the effect of in -hospital initiation of lipid-lowering therapy for patients with coronary heart disease on compliance and cardiovascular events.Method：This was a retrospective and follow-up study,which enrolled 398 patients with CHD.Result：The frequency of CHD patients taking lipid-lowering drugs was 79.5% before they discharged .For patients initiated lipid-lowering therapy in hospital,the proportion of patients continue to maintain lipid-lowering therapy was significantly higher than those who did not initiated lipid-lowering therapy （P〈0.01）after 17 months follow-up,the proportion of patients who detected serum lipid was also higher（P〈0.05） .The control rate of LDL-C was not statisitically difference between the two therapy groups （P〉0.05）,the incidence of cardiovascular events was also not statistically difference between the two therapy group（P〉0.05）.Conclusion ：For patients with coronary heart disease,in-hospital initiation of lipid-lowering therapy may improve loger-term treatment rates and patient compliance.