急性白血病初诊患者血细胞参数分析

Analysis of blood cell parameters of newly diagnosed acute leukemia patients

目的分析急性白血病初诊患者血细胞分析参数的特点,揭示血细胞分析参数在急性白血病诊断和分型中的意义,为临床医生初诊和检验人员血细胞分析复检提供依据。方法对已确诊的140例白血病初诊患者血细胞分析参数与参考值进行对照分析。结果急性白血病患者血细胞分析参数主要特点为血红蛋白(Hb)、红细胞比容(HCT)、中性粒细胞百分比(NEU%)、红细胞(RBC)、血小板(PLT)、嗜酸性粒细胞百分比(EOS%)降低,红细胞分布宽度(RDW)、淋巴细胞百分比(LYM%)、单核细胞绝对值(MONO)、嗜碱性粒细胞绝对值(BASO)、单核细胞百分比(MONO%)、白细胞(WBC)、淋巴细胞绝对值(LYM)升高;急性非淋巴细胞白血病参数主要特点为Hb、HCT、RBC、NEU%、PLT降低,RDW、BASO%、MONO%、MONO、BASO、中性粒细胞绝对值(NEU)升高;急性淋巴细胞白血病参数主要特点为Hb、HCT、NEU%、RBC、PLT、NEU、EOS%降低,LYM%、RDW、WBC、LYM升高。结论急性白血病患者血细胞分析参数特点为贫血且红细胞大小不一,PLT减少,NEU%和EOS%减低,淋巴细胞和单核细胞绝对值及百分数增高,BASO和WBC总数增高。急性非淋巴细胞白血病与急性淋巴细胞白血病的血细胞分析区别在于急性非淋巴细胞白血病以BASO%、MONO%、MONO、BASO、NEU升高为主要特点,急性淋巴细胞白血病则以LYM%、WBC、LYM升高,NEU、EOS%降低为主要特点。

Objective To study the features of blood cell parameters of newly diagnosed acute leukemia patients and to provide evidence for clinical doctors and laboratory technicians. Methods Blood cell parameters of 140 newly diagnosed acute leukemia patients were analyzed with the reference ranges. Results H b, HCT,NEU%,RBC, PI.T, EOS% decreased and RDW, LYM % , MONO, BASO, MONO%, WBC, LYM increased in acute leukemia. In acute non-lymphocytic leukemia（ANLL）, Hb, HCT, RBC, NEU%, PLT decreased while RDW, BASO%, MONO%, MONO,BASO and NEU increased. In acute lymphohlastic leukemia（ALL）, Hb, HCT, NEU%, RBC, PLT, NEU, EOS% decreased and LYM% ,RDW,WBC, LYM increased. Conclusion The common features of blood cell parameters of acute leukemia patients are Hb, HCT, NEU%, RBC, PLT, EOS% decreasing and RDW, LYM%, MONO, BASO, MONO%, WBC, LYM increasing. The major differences between ANLL and ALL are that BASO%, MONO%,MONO ,BASO, NEU increase in the former while LYM%,WBC, LYM increase and NEU, EOS% decrease in the later.