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Suramine对人结肠癌的裸鼠皮下移植瘤和SCID小鼠原位种植肝转移之生长、转移及肿瘤血管形成的抑制作用 被引量：3

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摘要 Suramine是最近发现的一个血管形成抑制剂,它是一个含有多硫基萘基脲的多价阴离子复合物,Suramine钠盐分子量为1429.2,结构式如下。
作者 王兵 唐思聪 汤睿
机构地区 上海第二医科大学附属第九人民医院普外科
出处 《大肠肛门病外科杂志》 1998年第3期43-45,共3页 Journal of Coloproctological Surgery
关键词 结肠癌 Suramine 皮下移植癌 肝转移瘤 肿瘤生长
分类号 R735.35 [医药卫生—肿瘤]
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参考文献5

  • 1Braddock PS,Hu DE,Fan TPD,et a1.A structure-activity analysis of antagonism of the growthfactor and angiogenic activity of basic fibroblast growth factor by suramine and related polyanions.Br J Cancer,1994,69:890-898.
  • 2Lapis K,Timar J,Papay J,et a1.Experiment metastasis inhibition by pretreatment of the host.Arch Geschwulstforsch.1990.60(2):97-102.
  • 3La Rocca,Stein CA,Fanesi R,et a1.Suramine in adrenal cancer:modulation of steroid hormone production,cytotoxicity in vitro,and clinical antitumor effect.J Clin Endocrinok Metab,1990,71(2):497-504.
  • 4La Roo cca RV.Danesi R,Cooper MR,et a1.Effect of surmain on human prostate cancer cells in vitro.J Urol,1991,145(2):393-398.
  • 5Gagliardi A,Hadd H,Collins DC.Inhibition of angiogenesis by suramine.Cancer Res,1992,15(18):5073.

同被引文献29

  • 1Bandaru S. Reddy,Yoshinobu Hirose,Ronald Lubet,et al. Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor,celecoxib, administered during different stages of carcinogenesis[J]. Cancer research,2000,60(2):293-297.
  • 2Tuyoshi Shoji,Hiroyuki Konno,Tatsuo Takanori Saka-guchi,et al. Orthotopic implantation of a colon cancer xenograft induces high expression of cyclooxygenase-2[J]. Cancer Letters. 2003,195:235-241.
  • 3Feldman M,McMahon AT. Do cyclooxygenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammstory drugs with less gastrointestinal toxicity[J]. Ann Intern Med,2000,132(1):134.
  • 4Xiao-Chun Xu. COX-2 inhibitors in cancer treatment and prevention,a recent development[J]. Anti-Cancer Drugs,2002,13:127-137.
  • 5Husain SS, Tarmawski AS,Imre LS,et al. NSAID inhibition of GI cancer growth :clinical implications and molecular mechanisms of action[J]. Am J Gastroentcrol,2002,97:542-553.
  • 6Jill M Herendeen,Celeste Lindley. Use of NSAIDs for the chemoprevention of colorectal cancer[J]. Ann Pharmacother,2003,37:1664-1674.
  • 7D.Bisacchi,PHD,R.Benelli,PHD,et al. Anti-angiogene-sis and angioprevention:mechanisms,problems and perspectives[J]. Cancer Detection and Prevention,2003,27:229-238.
  • 8Wang D,DuBois R N.Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch[J].Proc Natl Acad Sci USA,2004,101(2):415-416.
  • 9Cheng S H,Lin C H,Conway R,et al.Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression[J].Proc Natl Acad Sci USA,2004,101(2):591-596.
  • 10Bisacchi D,Benelli R,Vawzetto C,et al.Anti-angiogenesis and angioprevention:mechanisms,problems and perspectives[J].Cancer Detect Prev,2003,27(3):229-238.

引证文献3

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大肠肛门病外科杂志
1998年 第3期

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