山绿茶降压片治疗高血压药效学研究

Pharmacodynamics of Shanlucha Antihypertensive Tablets for the Treatment of Hypertension with Vertigo and Headache

目的:观察山绿茶降压片治疗高血压的药效学作用。方法:采用尾悬挂法、旷野实验法、对阈下剂量戊巴比妥钠的协同作用以及对大鼠血压、高脂血症的影响等实验,观察山绿茶降压片的药效学作用。结果:山绿茶降压片能明显减少小鼠自发活动;有协同阈下剂量戊巴比妥钠诱发小鼠睡眠的趋势;并有明显的降压及降血脂作用。结论:山绿茶降压片具有镇静、催眠、降压、降血脂作用。

Objective： To observe the Pharmacodynamics of Shanlucha Antihypertensive Tablets on the treatment of hypertension with vertigo and headache. Methods： Through the method of tail suspension test, the open field experiment, the synergetic effect with under threshould sodium pentobarbital and the effect on blood pressure and hyperlipemia in rats, the pharmacological role of Shanlucha Antihypertensive tablets on treatment of hypertension was observed. Results： Autokinesis of the mouse was decreased by Shanlucha Antihypertensive; it had a synergetic effect with under threshold sodium pentobarbital for the sleep of the mice, and it had significant sntihypertensive and hypolipidemic effect. Conclusions： Shanlueha Antihypertensive Tablets have an obvious effects on sedative, hypnogenesis, antihypertensive and hypolipidemic actions.