合肥市社区中老年人代谢综合征的影响因素及其生存质量评估

Influencing Factors of Metabolic Syndrome in Middle-aged or Aged People in a Community in Hefei and Evaluation of Their Quality of Life

目的探讨合肥市社区中老年人代谢综合征(metabolic syndrome,MS)的流行现状和影响因素,并对该人群的生存质量进行评估。方法采用整群抽样的方法,抽取合肥市董铺社区≥40岁的居民721人,其中男416人,女305人。MS诊断标准采用中华医学会糖尿病学分会关于MS的建议标准,对居民MS的影响因素采用多元逐步Logis-tic回归分析。采用世界卫生组织制定的生存质量量表(WHOQOL-BREF)对居民的生存质量进行评价,并比较MS患者与非MS患者的生存质量。结果以是否罹患MS为因变量,多因素Logistic回归分析显示,腰围、总胆固醇水平、高尿酸血症和糖尿病家族史是MS的主要影响因素。MS患者的生存质量在生理领域和整体感受方面的评分显著低于非MS患者,差异有统计学意义(P<0.05)。中年人的生存质量在心理领域和环境领域方面的评分显著低于老年人,而其社会关系领域评分显著高于老年人,差异均有统计学意义(P<0.05)。结论合肥市社区老年MS患者可能存在遗传倾向;控制腰围、总胆固醇和血尿酸水平,对预防MS、提高MS患者的生存质量有着重要意义。

Objective To investigate prevalence of metabolic syndrome （MS） and its influencing factors to evaluate the quality of life of middle - aged or aged people. Methods Using cluster sampling method, 721 residents （ 〉 40 years old, 416 males, 305 females） from a certain community were chosen as subjects. Taking the MS standards recommended by Chinese Medical Association Diabetology Branch as MS diagnostic criteria, a Logistic stepwise multiple regression analysis was performed on the influencing factors of MS. WHOQOL - BREF was used to evaluate the quality of life of the residents. Results Taking the risk of MS as dependent variable, multi -factor Logistic regression analysis showed that waist circumference （WC）, total choles- terol （TC） levels, hyperuricemia and family history of diabetes were the main factors influencing MS. In quality of life, the scores in physiological field and overall feeling were remarkably lower in MS patients than in Non - MS patients, the difference was significant （ P 〈 0. 05 ） . The scores in physiological field and overall feeling were lower, but in social relation higher in middle - aged people than in aged, the difference was significant （ P 〈 0. 05 ）. Conclusion Genetic predisposition may exist in middle - aged or aged people. Control of WC, TC, blood uric acid levels is of important significance in MS prevention and improvement of MS patients＇quality of life.