摘要
动物实验及临床研究均证实中性粒细胞对肺再灌注损伤的发展起着重要作用。其作用机制主要因为产生毒性氧代谢产物,分泌多种蛋白水解酶,阻塞肺微血管和释放炎性介质,致使更多中性粒细胞向损伤部位转移。
同被引文献12
-
1Rocket GM. Ischaemia/reperfusion, inflammatory responses and acute lung injury[J]. Tnorac, 1997, 52(10):841 - 842.
-
2Schutte H, Witzenrath M, Mayer K, et al. Short- term "preconditioning" with inhaled nitric oxide protects rabbit lungs against ischemia -reperfusion injury[J]. Transplantation, 2001, 72(8) : 1363 - 1370.
-
3Townsley MI, Korthuis RJ, Rippe B, et al. Validation of double vascular occlusion method for Pc, I in lung and skeletal muscle[J]. J Appl Phvsid, 1986, 61(1):127- 132.
-
4Featherstone RL, Chambers DJ, Kelly FJ. Ischemie preconditioning enhances recovery of isolated rat lungs after hypothennie preservation[J]. Ann Tnorac Surg, 2000, 69(1):237-242.
-
5Lockinger A, Schutte H, Walmrath D, et al. Protection against gas exchange abnormalities by pre - aerisolized PGE1, iloprost and nitropmsside in lung ischemia - reperfusion [ J ]. Transplantation, 2001, 71(2) : 185 - 193.
-
6Seibert AF, Haynes J, Taylor A. Ischemia- reperfusion injury in the isolated rat lung: role of flow and endogenous leukocytes[J]. Am Rev Respir Dis, 1993, 147(2):270-275.
-
7Fisher AB, Dodia C, Tan ZT, et al. Oxygen - dependent lipid peroxidation during lung ischemia[J]. J Clin Invest, 1991, 88(2) : 674 -679.
-
8Deeb GM, Grum CM, Lynch M J, et al. Neutrophils are not necessary for induction of ischamia - reperfusion lung injury[J]. J Appl Physiol,1990, 68(1):374-381.
-
9Stanb NC, Schhz EL, Albertine KH. Leucocytes and pulmonary microvascular injury[J]. Ann NY Acad Sci, 1982, 384:332 - 343.
-
10Gee MH, Albertine KH. Neutrophil - endothelial cell interactions in the lung[J]. Annu Rev Physiol, 1993, 55:227- 248.
-
1蒲江涛,廖斌,刘伦旭,戴天阳,杨峥.参附注射液对兔肺缺血再灌注细胞凋亡的保护作用及其机制探讨[J].细胞与分子免疫学杂志,2010,26(8):816-817. 被引量:3
-
2张松林,黄杰,涂仲凡.维生素C和维生素E对移植肺再灌注损伤保护作用的实验研究[J].中国急救医学,2003,23(4):215-216. 被引量:5
-
3谭毅,伍丽娜,杜晓东.姜黄素对大鼠肺缺血-再灌注损伤的保护作用[J].当代医学,2011,17(11):45-47. 被引量:2
-
4罗勤,罗向东,李晓辉,杨宗城.大鼠吸入性损伤血清对肺微血管内皮细胞的损伤作用[J].第三军医大学学报,1996,18(5):393-396.
-
5周勇安,刘锟,谷仲平,张涛.白细胞介素-10对大鼠移植肺再灌注损伤的保护作用[J].第四军医大学学报,2005,26(2):164-166. 被引量:8
-
6王雪峰,李君权,王胜发,李野,王巨,张铁娃.控制性再灌注防止肺再灌注损伤的研究[J].中华实验外科杂志,2003,20(5):460-461. 被引量:6
-
7区颂雷,陈玉平,张志泰,苏雷,宋飞强,耿新社,胡燕生,李昕.原位犬肺热缺血损伤的研究[J].中华器官移植杂志,1998,19(4):194-196. 被引量:4
-
8綦惠,赵丹慧,田伟.基质金属蛋白酶与椎间盘退变研究的新进展[J].中国脊柱脊髓杂志,2010,20(1):69-72. 被引量:13
-
9尹熙.乌司他丁对体外循环术患者围术期肺功能影响的系统评价[J].空军医学杂志,2015,31(3):181-184. 被引量:4
-
10杜振宗,任华,宋剑非,于洪泉,苗齐,张超纪.手术治疗肺动脉栓塞12例临床分析[J].北京医学,2006,28(3):145-147. 被引量:6