舟山地区脑性高危儿相关危险因素分析

An Analysis of Related High-risk Factors in Infantile Cerebral Palsy in Zhoushan

目的分析舟山地区小儿脑性瘫痪的高危因素,探讨早期干预措施。方法将2002—2009年来我院就诊的脑性瘫痪患儿136例作为观察组,选取同期同龄的正常患儿作为对照所有组,分析家族因素、母体因素和新生儿因素等近50项危险因素的差异。结果在脑瘫组136例中有高危因素的123例,>2项高危因素的98例;正常儿童组有高危因素的78例,>2项高危因素的46例,差异有统计学意义。其中以妊娠用药、早产、先兆子痫、宫内感染、生后窒息、低出生体重儿和非正常分娩等为最多见的病因。结论小儿脑瘫与妊娠期、新生儿期的各种高危因素密切相关,应认真做好产前、产时和产后的干预工作,降低小儿脑性瘫痪的发病率。

OBJECTIVE To analyze the high-risk factors of cerebral palsy in Zhoushan infants, and probe into the early-period precautionary measures. METHOD First, choose cerebral palsy infants who came to see the doctor between 2002 and 2009 as observation group, and choose normal infants of the same age as the control group. Second, analyze the differences concerning nearly 50 high-risk factors, including family factor, mother factor and newlyborn factor. RESULTS In the observation group, 123 of the 136 infants have some high-risk factor. The number of the children who have more than two high-risk factors is 98, while the number of the normal children who have some high-risk factor is 78. The children having more than two high-risk factors are only 46. This difference contains statistics significance. The most common causes are wrong medicine-taking during pregnancy, premature birth, toxemia of pregnancy, infection in utero, afterbirth suffocate, low birthweight, abnormal delivery, etc. CONCLUSION Cerebral palsy is closely related to different high-risk factors during pregnancy and early-period nursing. We must take precautionary meatures during ante partum, intrapartum and post partum in order to decrease the cerebral palsy rate.