红细胞免疫功能与AgNOR检测对肺结核病人的临床意义

Clinical significance of erythrocyte immune functions and AgNOR in tuberculosis

为探讨肺结核病人免疫功能的检测方法，采用郭峰法及银染方法对肺结核病人与健康对照者红细胞免疫功能及外周血淋巴细胞核仁组成区相关嗜银蛋白（ＡｇＮＯＲ）进行测定。结果表明肺结核病人红细胞免疫功能与外周血淋巴细胞ＡｇＮＯＲ颗粒总面积（ＧＡ）与细胞核面积（ＮＡ）之比（ＧＡ／ＮＡ）均明显低于正常对照组（Ｐ＜０．０１）。表明此检测可作为结核病人细胞免疫功能的一种方法，为结核病病人的免疫治疗、判断预后提供依据。

The significence and relationship of erythrocyte immune functions and argyrophilic protein in nucleolar or- ganizer regions(AgNOR)were studied.E-C3b and E-ICR were assayed by observing receptor rate.Granules area of AgNOR (GA)and nuclear area(NA)were studied by means of image analysis system.The results showed that E-C3b,GA/NA of tuberculosis patients were significantly lowere than those of the healthy group(P<0.001).However,the valuse of E-ICR were significantly higher than those of the control group (P<0.001).It is suggested that measurement of erythrocyte func- tions and AgNOR might be values in the diagnosis and prognosis assessment of tuberculosis.