穿透性角膜移植术式的新进展

Advances in penetrating keratoplasty technique

角膜移植术后排斥反应是目前导致角膜植片衰竭的主要原因。穿透性角膜移植仍是临床上广泛应用的术式之一。近年来，通过改良穿透性角膜移植术式达到降低角膜移植排斥发生率的方法越来越受到广大眼科医师的重视。通过文献归纳，分析了飞秒激光塑形高帽状结构的穿透性角膜移植（PKP）、手工式高帽式的穿透性角膜移植、半高帽状的穿透性角膜移植术等角膜移植技术的研究进展。

Rejection after corneal transplantation is currently the lead of the main reasons for corneal graft failure. Penetrating keratoplasty （PK） is still one of the gold standard surgeries for these patients. In recent years, improving the surgical techniques to reduce the incidence of corneal allograft rejection has been the way to more and more attention to the majority of ophthalmologists. To generalize and analyze the recent research of new technologies of femtosecond laser shaped penetrating keratoplasty of top-hat configuration （FS-TH-PKP）, manual top-hat wound configuration for penetrating keratoplasty （M-TH-PKP）, and halftop-hat penetrating keratoplasty （HTH-PKP） surgeries.