莫西沙星治疗老年社区获得性肺炎中的疗效

The action of moxifloxacin in the elderly community-acquired pneumonia

目的评估莫西沙星治疗老年社区获得性肺炎的有效性及其安全性。方法将2008年1月至2009年3月在我科住院的老年社区获得性肺炎分治疗组和对照组,其中治疗组随机抽取40例患者,对照组随机抽取20例患者。治疗组给予莫西沙星400 mg静脉滴注qd;对照组给予左氧氟沙星300 mg静脉滴注qd,疗程为2周。观察临床疗效及其不良反应。结果治疗组有效率87.50%,细菌清除率为82.75%,不良反应12.50%。结论莫西沙星在老年社区获得性肺炎中有效率高,不良反应少。

Objective To evaluate the effectiveness and safety of moxifloxacin in the elderly community-acquired pneumonia. Methods The patients with elderly community-acquired pneumonia who were in hospital from January 2008 to March 2009 were randomly selected and divided into a treatment group（n = 20）and a contrast group（n = 20）. The treatment group were given moxifloxaein 400 mg intravenous drip qd and the contrast group were given 300 ing of levofloxacin qd. The period of the treatment was two weeks. Clinical effects and adverse reactions were observed. Results The effective rates of the treatment group were 87.50% , the rates of bacterial clearance were 82.75%. The rates of adverse reactions were 12.50%. Conclusion Moxifloxaein in the elderly community-acquired pneumonia has high effective rates and less adverse reactions.