86例早期胃癌预后因素分析

Prognostic factors of 86 cases of early gastric cancer

目的:探讨分析对早期胃癌预后影响的因素。方法:回顾性分析1997年1月～2007年1月我院收治86例早期胃癌患者的临床资料及术后随访资料,统计分析早期胃癌影响预后的因素。结果:本组早期胃癌病例5年生存率为90.9%,其预后主要与肿瘤大小、淋巴结转移相关,肿瘤直径<2cm、2～4cm、>4cm以上5年生存率分别为100.0%、71.6%,50.5%,有淋巴结转移者5年生存率(73.4%)明显低于无淋巴结转移者(91.3%)。相关性分析表明年龄、性别、病理分型与预后因素间无明显相关性。结论:毕Ⅰ或毕Ⅱ式根治术后患者,淋巴结转移、肿瘤大小是早期胃癌重要的预后因素,对肿瘤直径大、淋巴结转移广泛的早期胃癌患者应采用以根治术为主的综合治疗方案,对指导早期胃癌预后及手术选择有实际应用价值。

Objective： To discuss and analyze the factors affecting the prognosis of early gastric cancer. Methods： A retrospective analysis from January 1997 to January 2007 in our hospital admitted 86 cases of early gastric cancer clinical data and postoperative follow-up data, to statistical analyze the prognostic factors of early gastric cancer. Results： 5-year survival rate of early gastric cancer in this group was 90.9%, the prognosis factors mainly related to tumor size, lymph node metastasis, diameter〈2 cm, 2-4 cm,〉4 cm, 5-year survival rate were 100.0%, 71.6%, 50.5% respectively, and 5-year survival rate with lymph node metastasis （73.4%） was lower than that without lymph node metastasis （91.3%）. Correlation analysis table of age, gender, pathological classification and prognostic factors, there was no significant correlation. Conclusion： Billroth＇s I or Ⅱ radicalsurgery patients, lymph node metastasis, tumor size are important prognostic factors in early gastric cancer, lymph node metastasis of tumor diameter, large range of early gastric cancer with radical surgery should be based on comprehensive treatment program and have practical application value to guide early gastric cancer prognosis and surgical options.