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miRNA与乳腺癌转移 被引量：8

MiRNA and breast cancer metastasis
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摘要 肿瘤转移是造成乳腺癌患者死亡的主要原因。最新研究表明，一些miRNA在转录后水平调控乳腺癌转移相关基因的表达，与乳腺癌的侵袭和转移密切相关。本文针对参与调控乳腺癌侵袭和转移的miRNA及其作用机制做以综述。 Most deaths of breast cancer patients may be caused by the development of metastases. The latest research suggest that some miRNAs regulated gene expressions related with breast cancer metastasis at post-transcriptional level, which was closely related to invasion and metastasis of breast cancer. This review mainly dieussed the miRNA involved in regulation of invasion and metastasis of breast cancer and their molecular mechanisms.
作者 李志华 罗永辉
机构地区 南昌市第三医院乳腺疾病防治中心
出处 《国际外科学杂志》 2010年第1期46-48,共3页 International Journal of Surgery
关键词 MIRNA 乳腺癌 转移 基因调控 MiRNA Breast cancer Metastasis Gene control
分类号 R737.9 [医药卫生—肿瘤] R394 [医药卫生—医学遗传学]
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共引文献248

同被引文献74

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国际外科学杂志
2010年 第1期

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