陕西农村母乳喂养儿肠道菌群与体格发育研究

A study on influence of intestinal microflora on growth and development of breast-fed infants aged 0 - 18 months in rural areas of Shaanxi province

目的探讨陕西农村地区0～18个月婴幼儿肠道菌群与体格发育的关系。方法采取随机抽样的方法对55名0-18个月母乳喂养的健康婴幼儿进行粪便5种菌群的定量检测与体格发育的测量，菌群检测采用细菌培养法，调查数据采用SPSS13．0软件完成统计分析。结果调查地区婴幼儿肠道有益菌双歧杆菌和乳酸菌的构成比例较低，肠道乳酸菌与身长（r=0．379，P〈0．01）、体重（r=0．296，P〈0．05）显著正相关。营养优良儿肠道粪便中双歧杆菌与肠杆菌数量的比值（B／E值：6．87）显著高于营养正常儿（B／E值：1．05）。结论肠道乳酸菌及较高的定植抗力对婴幼儿的体格发育有很大的促进作用，应通过改善肠道菌群促进婴幼儿的生长发育。

Objective To explore relation between intestinal mieroflora and growth and development of infants and young children aged 0 - 18 months in rural areas of Shaanxi province. Methods In cluster sampling method, 55 healthy beast-fed infants aged 0 - 18 months were selected randomly. They received physical examination and five kinds of bacteria flora in their faeces （ bacteroides, bifidobacterium, enterobacter, C. perfringens and lactobacillus） were detected quantitatively in culture method. The data were statistically analyzed by SPSS 13.0 software. Results The constituents of bifidobaeterium and lactobacillus in intestinal tract of infants in rural areas investigated were both lower. There were significantly positive correlations between lactobaeillus and body length （ r = 0.379, P 〈 0.01 ） and body weight （ r = 0. 296, P 〈0.05） of the infant. The ratio of bifidobacterium/lactobacillus （B/E） of infants with better nutritional status（ B/E = 6.87） was significantly higher than that of infants with normal nutritional status （ B/E = 1.05 ）. Conclusion The more number of intestinal lactobacillus and its higher intestinal implantation resistance may promote growth of the infant. In order to promote growth of the infants, their intestinal microflora should be improved.