摘要
以甲醇为溶剂,L-酒石酸托特罗定的最大吸收在283nm处,建立了紫外分光光度法测定L-酒石酸托特罗定含量的方法,酒石酸托特罗定的浓度在2.208×10-5—4.289×10-4mol/L范围内,吸光度和浓度呈良好的线性关系,该法的加标回收率为97.7%。方法操作简单,重现性好,准确度高,用于进口L-酒石酸托特罗定片剂的含量测定,结果满意。
A new method for the determination of the content of tolterodine-L-tartrate was developed by UV spectrophotometry with methanol as solvent at 283nm. The absorbance is proportional to the concentration in the range of 2. 208 × 10^-5--4. 289 ×10^-4mol/L,and the recovery in real sample was 97. 7%. This method is well reproducible, accurate, simple and reliable. It is applicable to determine the content of the tablet of tolterodine-L-tartrate with satisfactory results.
出处
《光谱实验室》
CAS
CSCD
北大核心
2010年第1期277-279,共3页
Chinese Journal of Spectroscopy Laboratory
基金
上海市教委科研创新项目(编号:09YZ374)
上海工程技术大学校友展基金(编号:2008XY32)
