摘要
炎性乳腺癌(inflammatory breastcancer,IBC)虽为一种较少见的乳腺恶性肿瘤,但由于它的高侵袭性、高转移复发率和低无病生存率而引起肿瘤学家的关注。而以往病理学者多认为IBC是一种以临床表现为特征的乳腺癌,对其缺乏重视。近年来国外学者们对于其概念和意义有了新的认识,在分子病理学方面的研究进展也很快。但国内研究尚少心剖。笔者拟从几方面介绍其新进展,希望能引起同道们的研究兴趣。
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2010年第1期59-62,共4页
Chinese Journal of Pathology
参考文献28
-
1Resetkova E. Pathologic aspects of inflammatory breast carcinoma : part 1. Histomorphology and differential diagnosis. Semin Oncol, 2008,35 ( 1 ) :25-32.
-
2董慧明,刘刚,吴炅,陆劲松,罗建民,沈镇宙,邵志敏.MAPK信号传导通路对人炎性乳腺癌细胞系侵袭能力的影响[J].中国癌症杂志,2005,15(5):426-428. 被引量:5
-
3陈庆永,蒋春舫,陈剑英,王春友.外源性PTEN基因转染对炎性乳腺癌MDA-MB-468细胞株体外生物学行为的影响[J].华中科技大学学报(医学版),2006,35(3):358-361. 被引量:1
-
4Tavassoli FA, Devilee P. World Health Organization classification of tumours. Pathology and genetics of tumours of the breast and female genital organs. Lyon : IARC Press, 2003 : 102-112.
-
5Ferrara AR. Inflammatory breast cancer : challenges and developments. Radiol Technol, 2008, 80(1) :49M-60M.
-
6Tavassoli FA, Eusebi V. Atlas of tumor pathology. Series 4. Tumors of the mammary gland. Washington DC : AFIP ,2009 : 155- 156.
-
7Kidwell AK. Inflammatory breast cancer: a race against time. JAAPA, 2007, 20(9):40-44.
-
8Charafe-Jauffret E, Tarpin C, Bardou V J, et al. Immunophenotypic analysis of inflammatory breast cancers : identification of an ' inflammatory signature'. J Pathol, 2004, 202 ( 3 ) :265-273.
-
9Gong Y. Pathologic aspects of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotype. Semin Oncol, 2008, 35(1) :33-40.
-
10Ben Hamida A, Labidi IS, Mrad K, et al. Markers of subtypes in inflammatory breast cancer studied by immunohistochemistry: prominent expression of P-cadherin. BMC Cancer, 2008, 8 ( 1 ) : 28.
二级参考文献17
-
1Berx G, van Roy F. The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression [ J]. Breast Cancer Res,2001,3(5 ) :289-293.
-
2Alpaugh ML, Tomlinson JS, Shao ZM, et al. A novel human xenograft model of inflammatory breast cancer [ J ] . Cancer Res, 1999,59(20) :5079-5084.
-
3Colpaert CG, Vermeulen PB, Benoy I, et al. Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression [ J ] . Br J Cancer, 2003,88 ( 5 ):718-725.
-
4Kleer CG, van Golen KL, Braun T, et al. Persistent E-cadherin expression in inflammatory breast cancer [ J ]. Mod Pathol,2001,14(5) :458-464.
-
5Tomlinson JS, Alpaugh ML, Barsky SH. An intact overexpressed E-cadherin/alpha, beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma [ J ]. Cancer Res,2001,61 ( 13 ) :5231-5241.
-
6Holvoet S, Vincent C, Schmitt D, et al. The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes [ J ]. Exp Cell Res,2003,290 ( 1 ): 108-119.
-
7Yao J, Xiong S, Klos K, et al. Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-betal in human breast cancer cells [ J ]. Oncogene,2001,20 (56) . 8066-8074.
-
8Sanceau J, Truchet S, Bauvois B. Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in Ewing's sarcoma cells [ J ]. J Biol Chem, 2003,278 ( 38 ):36537 -36546.
-
9LI J, YEN C, LIAW D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer[J]. Science, 1997,275(5308):1943-1947.
-
10STECK P A,PERSHOUSE M A,JASSER S A,et al. Identification of a candidate tumor suppressor gene, MMAC1 ,at chromosome 10q23.3 that is mutated in multiple advanced cancers[J].Nat Genet, 1997,15(4) : 356-362.
共引文献4
-
1陈瑛,杨帆,王芳.炎性乳腺癌的X线诊断[J].实用临床医学(江西),2009,10(1):92-93. 被引量:4
-
2许瀚,李孟圈.ERK信号转导通路与乳腺癌关系的研究进展[J].肿瘤基础与临床,2010,23(1):80-82. 被引量:1
-
3王莉萍,陈韵彬,陈英.炎性乳癌的钼靶X线诊断[J].现代医用影像学,2011,20(3):193-194.
-
4谭米多,刘力,刘国文.E-cadherin与炎性乳腺癌关系的研究进展[J].肿瘤药学,2012,2(4):249-252. 被引量:4
同被引文献7
-
1陈霞,刘宝冬,左飞伍,李颖,屈昕,尚滔.炎性乳腺癌的超声诊断[J].中国超声医学杂志,2006,22(9):707-708. 被引量:13
-
2王娟,闫秀欣,许一多,左晓文,林春梅,于敦祥.高频彩色多普勒超声对炎性乳腺癌诊断价值探讨[J].中国妇幼保健,2007,22(11):1537-1538. 被引量:8
-
3CA Droubliac. Inflammatory carcinoma of the breast:a correlation of clinical, radiological and pathologic find- ings[J]. Ann Surg, 1976(184) :217 -222.
-
4Hahn SY, Choi HY, Park SH, et al. Lymphangioma and lymphangiectasia of the breast mimicking inflammatory breast cancer [ J ]. Ultrasound Med, 2011 ( 6 ) : 863 - 865.
-
5Le MG, Arriagrada R, Bahi J, et al. Are risk factors for breast cancer similar in women with inflammatory breast cancer and in zhose with non - inflammatory breast canc- er [ J]. Breast,2006( 15 ) :355 - 362.
-
6陈瑛,杨帆,王芳.炎性乳腺癌的X线诊断[J].实用临床医学(江西),2009,10(1):92-93. 被引量:4
-
7肖春花,龚芸,付丽.炎性乳腺癌分子研究及治疗进展[J].中华乳腺病杂志(电子版),2010,4(2):22-25. 被引量:3
-
1杨柯君.转移性乳腺癌一线治疗新选择[J].上海医药,2014,35(4):50-50.
-
2汤杨明,白青伟,林金盈,温宗华,蓝梅,李勇敢,周瑞莲.老年人EB病毒阳性弥漫性大B细胞淋巴瘤6例临床分析[J].临床血液学杂志,2014,27(4):600-602. 被引量:3
-
3辛建会,张雪鹏.MCF-7乳腺癌细胞的国内研究进展[J].中国民族民间医药,2014,23(8):47-48.
-
4胡晓清,舒畅.内镜技术在头颈肿瘤手术中的应用[J].国际耳鼻咽喉头颈外科杂志,2012,36(1):36-39.
-
5唐金海,陈伟贤.乳腺癌分子分型及其指导下的个体化治疗[J].中国癌症防治杂志,2013,5(3):187-191. 被引量:8
-
6陆莉,肖秀娣,徐雪松,武正炎.原发性双侧乳腺癌11例临床分析[J].江苏医药,2010,36(15):1851-1852. 被引量:2
-
7左丽,张凤春,徐迎春,陶莉.吉西他滨联合顺铂二、三线治疗晚期三阴乳腺癌临床观察[J].实用肿瘤杂志,2011,26(3):278-281. 被引量:18
-
8乐承艺.C-erbB-2癌基因产物的表达在乳腺癌诊断及预后方面的意义[J].华夏医学,1994,7(3):79-81.
-
9孟迪,黄焰.三阴性乳腺癌分子标志物的研究进展[J].中华乳腺病杂志(电子版),2013,7(5):45-49. 被引量:2
-
10马蓉,姚宇锋,龚建平,秦建伟,唐金海.雄激素受体在三阴性乳腺癌中的表达及其预后价值[J].肿瘤预防与治疗,2013,26(3):122-124. 被引量:3