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Cripto-1蛋白在乳腺癌的发生、发展及靶向治疗中的研究进展 被引量:2

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摘要 乳腺癌的局部侵袭和远处转移是其预后不良、长期生存率低的主要因素,并且是一个多因素参与的复杂过程,癌细胞的运动、迁移是肿瘤转移的关键步骤之一。寻找与癌细胞迁移有关的基因,研究它们对乳腺癌转移的作用,有助于阐明乳腺癌转移的分子机制,并为防治肿瘤转移提供新的思考位点和理论依据。Cripto-1蛋白是一种与肿瘤侵袭和转移密切相关的蛋白质,本文中将对其在乳腺癌发生、发展及靶向治疗方面的研究进展做一综述。
出处 《中华病理学杂志》 CAS CSCD 北大核心 2010年第1期66-68,共3页 Chinese Journal of Pathology
基金 国家自然科学基金(30600225) 教育部长江学者乳腺癌创新团队支持计划(IRT0743)
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参考文献17

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