2微米激光对人前列腺组织汽化比率的体外实验研究

An ex vivo study on the vaporization ratio of the prostatic tissue lased by the 2 micron laser

目的体外观察2μm激光对良性增生前列腺组织的汽化、清除比率，探讨估量经尿道2μm激光前列腺汽化切除术中前列腺组织清除量的方法。方法经开放手术获取新鲜前列腺组织标本共9个，立即称量质量，模拟经尿道2μm激光前列腺汽化切除术条件下进行体外前列腺汽化切除术，每个腺体均被完全切割至直径小于1．0cm的碎块。术后立即称量收集到的全部前列腺组织碎块质量，计算出丢失的前列腺组织质量，进一步分别计算出收集到的前列腺组织质量及丢失前列腺组织质量在前列腺腺体标本质量中所占的比例，并对收集到的前列腺组织质量与整个腺体质量问的相关性进行分析。结果相对于前列腺腺体标本质量，收集到的前列腺组织质量所占比例为（34．5±1．5）％，丢失前列腺组织质量所占比例为（65．6±1．5）％。收集到的前列腺组织质量与前列腺腺体标本质量成线性关系。结论体外模拟经尿道2μm激光前列腺汽化切除术的条件下，根据所收集到前列腺组织质量可以计算出前列腺组织的汽化、切除比率，并可进一步推知相应的前列腺组织清除量。

Objectives To observe the vaporeseetion efficiency of the 2 micron laser to the prostatic gland in benign prostatic hyperplasia, and investigate the method of estimating the amount of the vaporeseeted prostatic tissues during transurethral vaporeseetion of the prostate using the 2 micron laser system in the treatment of benign prostatic hyperplasia. Methods Total 9 fresh prostatic gland specimens were obtained from patients with BPH under open surgical procedures, and vaporesected under a simulated transurethral environment with the 2 micron laser system immediately after weighted. Energies and time consumptions were noted, collections of vaporeseeted tissue specimens and the remnants of the prostatic glands were weighted after the procedures. The ratios of the vaporized tissues and the collected tissues to the whole vaporesected tissues were calculated respectively. The vaporeseetion efficiency of the 2 micron laser to the prostatic tissues was also calculated. Results Among the total lost tissues, about （65.6 ±1.5 ） percent of which were that of vaporized, and nearly （34. 5 ± 1.5 ） percent were reseeted. Linear correlation between the weight of collected prostatic tissue（x） and the weight of prostatic gland specimens（y） could be defined as a formula of [ y = 3. 245x - 6. 475 （ t = 15. 097, P = 0. 000 ） ]. Conclusion The amounts of the whole prostatic tissues removed by the 2 micron laser could be calculated from the collected resected prostatic specimens under a simulated transurethral surgical procedure.