糖尿病肾病维持性血液透析患者骨质疏松情况研究

Clinical study of osteoporosis in diabetic nephropathy patient on maintenance hemodialysis

目的探讨糖尿病肾病(diabetic nephropathy,DN)维持性血液透析患者骨质疏松情况。方法选择维持性血液透析患者60例,其中DN24例,非糖尿病肾病36例,采用双能X线骨密度测定仪测定腰椎及股骨。结果DN组较非糖尿病肾病组腰椎及股骨BMD明显降低(P<0.01),DN组严重骨质疏松及骨折的发生率明显增高(P<0.05)。结论DN维持血液透析患者骨质疏松及骨折发生率高。

Objective To study osteoporosis incidence in diabetic nephropathy patients on maintenance hemodialysis. Methods： 60 cases maintenance hemodialysis patients, 24 cases of the total with diabetic nephropathy（DN） ,36 cases with non-diabetic nephropathy and their lumbar and femoral bone mass density （BMD） detected by dual energy X-ray absorptiometry. Results： lumbar and femoral BMD in DN group is obviously fewer than non-diabetic nephropathy group （ P 〈 0. 01 ） , serious osteoporosis and bone fracture incidence in DN group is obviously higher than non-diabetic nephropathy group（P 〈 0.05 ）. Conclusion osteoporosis and bone fracture incidence in DN on maintenance hemodialysis is obviously high.