摘要
1例24岁女性患者,因治疗非霍奇金淋巴瘤,静脉输入利妥昔单抗注射液0.1g+0.9%氯化钠注射液100mL,滴速为50mL·h-1,10min左右出现面色潮红、心慌、胸闷、憋气,BP105/60mmHg,HR120次·min-1,R24次·min-1,立即调节输液速度20mL·h-1,给予鼻导管吸氧,地塞米松钠、盐酸异丙嗪、注射用甲泼尼龙琥珀酸钠治疗后,不适症状缓解并逐渐消失。
A 24-year-old female received an intravenous infusion ofrituximab 0.1 g, which was dissolved in 100 mL of 0.9% sodium chloride, with the drip speed of 50 mL·h^-1, in the treatment of non Hodgkin lymphoma. About 10 minutes after infusion start, the patient developed flushed face, cardiopahnus, dyspnea and breathlessness, with blood pressure 105/60 mmHg, heart rate 120 beats per minute and respiratory frequency 24 beats per minute. The drip speed was adjusted to 20 mL·h^-1 immediately and the patient was treated with oxygen inhalation by nasal catheter and dexamethasone, promethazine hydrochloride and methylprednisolone sodium succinate for injection. The uncomfortable symptoms caused by rituximab were relieved and disappeared gradually.
出处
《中国药物应用与监测》
CAS
2010年第1期61-62,共2页
Chinese Journal of Drug Application and Monitoring
