新兵人群风疹病毒抗体水平回顾性血清流行病学调查

A Retrospective Seroepidemiological Study of Rubella Antibody Level in Recruits

目的了解入伍新兵人群中风疹病毒IgG抗体的流行分布情况,为今后预防提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对北京军区近4年来自8个省市的360名入伍新兵血清进行了风疹病毒IgG抗体检测,统计分析其阳性率。结果发现各年间入伍新兵血清中风疹病毒IgG抗体呈逐年增高趋势,为91.23%～100.00%,平均95.56%;地区间无显著差别,河南省(100.00%)、甘肃省(97.67%)、江西省(97.50%)和四川省(97.02%)较高,江苏省(91.23%)、广西省(92.00%)和河北省(94.00%)较低;入伍前工作与否,抗体阳性检出率无显著性差别。结论入伍新兵人群中风疹病毒IgG抗体阳性率为91.23%～100.00%,并呈逐年增高趋势,地区间差异无统计学意义;新兵人群风疹病毒抗体水平较高,形成了免疫保护屏障。

[ Objective ] To understand the distribution of rubella antibody IgG in recruits, and provide scientific evidence for further prevention and control of the disease. [ Methods] A seroepidemiological study was conducted by using ELISA. Serum samples of 360 recruits , who came from 8 provinces during the past 4 years, were tested for rubella antibody IgG, and the overall positive rate was analyzed statistically. [ Results] Serum rubella antibody IgG levels of new recruits increased annually, which ranged from 91.23% to 100.00% with a average rate of 95.56% ; regional difference did not existed significantly, the higher level were found in recruits from Henan （ 100.00% ） , Gansu （ 97.67% ） , Jiang＇xi （ 97.50% ） , Sicbuan （ 97.02% ） , and lower level from Jiangsu （ 91.23% ） , Guangxi （ 92.00% ） and Hebei （ 94.00% ）. There was no significant difference between the antibody IgG positive rate of the recruits with occupation background or not before their recruitment. [ Conclusion] The positive rate of rubella antibody IgG is increasing annually in the recruits, which ranges from 91.23% to 100.00%. The positive rate of antibody IgG is not significantly different between provinces. The higher rubella virus antibody levels in recruits have formed the immune protective harriers.