石家庄市从业人员ALT异常者情况分析

Analysis of Employees with Abnormal ALT in Shijiazhuang City

目的了解石家庄市从业人员ALT异常者分布和肝炎病毒感染状况。方法采用紫外—乳酸脱氢酶法对92628名从业人员的血清进行ALT检验和HBsAg检测,对其中1486例ALT异常者再次抽血进行甲型和丙型肝炎血清标志物检验,同时进行ALT检测。结果从业人员中ALT异常率为1.60%,其中男性高于女性,31～40岁年龄组中异常率最高,行业之间比较无差异。甲型肝炎为零感染率,乙型肝炎和丙型肝炎感染率均为1.17%。结论从业人员中ALT异常者同病毒性肝炎的感染具有一定相关性,应重视从业人员的ALT检测工作。

[ Objective ] To study the distribution of abnormal alanine transaminase （ALT） and the infection status of hepatitis virus among employees in Shijiazhuang city. [ Methods] ALT and HBsAg were tested in serum samples of 92628 employees by ultravioletlactate dehydrogenase method. 1486 cases with abnormal ALT were detected serum virus labels of hepatitis A and hepatitis C, and the ALT was tested at the same time. [Results]The abnormal rate of ALT was 1.60% among the employees, and that of male employees was higher than that of the female employees. The abnormal rate of ALT in 31 -40 years group was the highest. There was no significant difference between different vocations. Nobody was infected by hepatitis virus A, and the infection rate of hepatitis virus B and hepatitis virus C were both 1.17%. [ Conclusion] There was a correlation between abnormal ALT and infection of hepatitis virus among the employees, so the detection of ALT among the employees is necessary.