早期鼻肠管肠内营养辅以肠外营养支持在重型颅脑损伤中的应用

Application of enteral nutrition supplemented with nasal intestine parenteral nutrition in severe craniocerebral injury

目的:观察早期鼻肠管肠内营养辅以肠外营养对重型颅脑损伤患者的疗效。方法:将76例重型颅脑损伤患者随机分为实验组与对照组各38例,实验组留置鼻肠管,对照组留置鼻胃管,均给予早期肠内营养辅以场外营养的营养支持方式,观察两组生活指标、胃肠道耐受及并发症情况。结果:营养支持后7d血清蛋白呈上升趋势,但两组比较差异无统计学意义(P>0.05);两组血糖均较营养支持前下降,两组比较差异有统计学意义(P<0.01);实验组并发症发生率比对照组明显降低(P<0.05)。结论:重型颅脑损伤病患者早期鼻肠管肠内营养辅以场外营养支持方式,可以明显改善营养状况,减少并发症的发生。

Objective： To observe the therapeutic effects of enteral nutrition supplemented with nasal intestine parenteral nutrition in severe craniocerebral injury. Methods： 76 patients with severe cranioce rebral injury were randomly divided into experimental group and control group by half. On the basis of supportive therapy of enteral nutrition, naso intestinal and nasogastric tube feeding were separately applied for the experimental group and the control group. Life indicators, gastrointestinal tolerance, and complications of these two groups were observed and compared. Results： After 7 days of nutrition supportive therapy, serum protein levels of the two groups both showed increase tendency with no significant difference being found between them （P〉0. 05）; while blood glucose level decreased and showed significant difference between the two groups （P〈0. 01）; the complication incidence of the experimental group was lower than that of the control group （P〈0. 05）. Conclusion： Supportive therapy of naso-intestinal and nasogastric tube feeding can improve the nutrition status and decrease the complication incidence for patients with severe craniocerebral injury.