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心力衰竭患者血浆脑钠肽水平检测分析 被引量:7

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摘要 目的探讨心力衰竭患者血浆脑钠肽(BNP)水平与心功能的关系。方法选择心力衰竭患者120例,NYHA分级心功能Ⅱ级30例、Ⅲ级42例、Ⅳ级48例。检测患者血浆BNP水平,同时给予心脏彩色多普勒超声仪检查左室舒张末期内径(LVEDD)及左室射血分数(LVEF)。另选择健康查体者112例作为对照组。结果心衰组BNP、LVEDD及LVEF分别为(456.43±202.70)pg/ml、(59.24±9.20)mm、(32.26±7.18)%,对照组分别为(25.23±7.30)pg/ml、(41.56±6.74)mm、(58.85±9.75)%。心衰NYHA心功能Ⅱ、Ⅲ、Ⅳ级患者BNP水平分别为(188.32±66.36)、(432.26±102.82)、(1236.31±620.58)pg/ml。两组BNP、LVEF比较差异有统计学意义(P<0.01),心衰患者不同心功能分级间BNP水平比较差异有统计学意义(P均<0.01)。结论血浆BNP浓度与心力衰竭的严重程度有关。
作者 李松美
机构地区 蓬莱市中医院
出处 《山东医药》 CAS 北大核心 2009年第49期36-37,共2页 Shandong Medical Journal
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参考文献6

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