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急性脑梗死患者抵抗素变化与其危险因素的关系 被引量:4

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摘要 目的探讨急性脑梗死(AC)患者抵抗素变化与其危险因素的关系。方法选择68例AC患者(AC组)与40例体检健康者(对照组),用ELISA法检测其血清抵抗素、空腹胰岛素、胰岛素抵抗指数、血脂等,并分析血清抵抗素水平与其他检测指标的相关性。结果与对照组比较,AC组血清抵抗素明显升高(P<0.01);AC组抵抗素水平与BMI、空腹胰岛素、胰岛素抵抗指数呈正相关,与HDL-C呈负相关(P均<0.05)。结论高抵抗素血症可能是AC重要的危险因素。
出处 《山东医药》 CAS 北大核心 2009年第49期39-40,共2页 Shandong Medical Journal
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  • 1各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33022
  • 2Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes[ J]. Nature, 2001,409(6816) :307.
  • 3李胜男.血清抵抗素、TNF-α与2型糖尿病及胰岛素抵抗的相关研究[J].山东医药,2009,49(12):77-78. 被引量:7
  • 4Asano T, Sakosda H, Fujishiro M, et al. Physiological significance of resistin and resistin-like molecules in the inflammatory process and insulin resistance [J]. Curr Diabetes Rev, 2006,2(4) :449- 454.
  • 5Calabro P, Samudio I, Willerson JT, et al. resistin promotes smooth muscle cell proliferation through activation of extracelular signal-regulated kinase 1/2 and phosphatidy linositol 3-kinase pathways[J]. Circulation, 2004,110(21): 3335 -3340.
  • 6Jung HS, Park KH, Cho YM, et al. Resistin is secreted from macrophages in atheromas and promotes athero sclerosis[ J]. Cardiovasc Res, 2006,69( 1 ) :76-85.

二级参考文献7

  • 1Patel L, Buckels AC, Kinghorn IJ, et al. Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators [ J]. Biochem Biophys Res Commun, 2003,300(2) :472-476.
  • 2Hotamisligil GS, Spiegelman BM. Tumor necrosis factor alpha: a key component of the obesity [ J ]. Diabetes, 1994,43 ( 11 ) : 1271 - 1278.
  • 3Saghizadeh M, Ong JM, Garvey WT, et al. The expression of TNF alpha by human muscle. Relationship to insulin resistance [ J ]. J Clin Invest, 1996,97(4) :1111-1116.
  • 4Haffner SM, Gonzalez C, Miettinen H, et al. A prospective analysis of the HOMA model. The Mexico City Diabetes Study [ J ]. Diabetes Care, 1996,19(10) :1138-1141.
  • 5Steppan CM, Brown EJ, Wright CM, et al. A family of tissue-specific resistin-like molecules [ J]. Proc Natl Acad Sci USA, 2001,98 (2) :502-506.
  • 6Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes [J]. Nature, 2001,409(6818) :307-312.
  • 7李光伟.2型糖尿病系列讲座 第三讲:胰岛素敏感性评估及其在临床研究中的应用[J].中华内分泌代谢杂志,2000,16(3):198-200. 被引量:195

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