经皮无水乙醇注射联合肝动脉化疗栓塞治疗少血供肝癌

Hypovascular liver carcer treated by PEIT(Iodic oil injection therapy)combined with TACE(Transcatheter hepatic arterial chemoembilization)

目的探讨B超引导下经皮肝穿刺瘤内注射无水乙醇(PEI)联合肝动脉化疗栓塞(TACE)治疗少血供肝癌的疗效。方法经组织学及三期CT增强扫描确诊的64例少血供肝癌分为两组:研究组(A组)34例,先行TACE,再行B超引导下PEI;对照组(B组)30例,仅行TACE治疗。结果研究组半年、1年、2年生存率分别为88.2%、63.3%、42.1%,近期有效率为73.5%。对照组半年、1年、2年生存率分别为60%、44.4%、25.0%,近期有效率为43.3%。两组间比较生存率和近期有效率差异均有统计学意义(P<0.01)。结论少血供肝癌TACE+PEI疗效优于单纯TACE,是一种值得推荐的治疗方法。

Objective To investigate the efficacy of percutaneous ethanol and iodic oil injection therapy （PEIT） combined with transcatheter hepatic arterial chemoembolization （TACE） in treating hypovascular liver cancer. Methods 64 patients who were diagnosed as hypovascular liver cancer by liver biopsy and 3 stages spiral CT scanning were divided into 2 groups ： group TACE ＋ PEII （ 34 cases）, treated with TACE and then followed by uhrasound - guided PEII, group TACE （30 cases） treated with TACE. Results After treatments, half - year, 1 - year and 2 - year survival rates of group TACE ＋ PEII and group TACE were 88.2%, 44.4% ; 63.3%, 42.1% ; 60%, 25.1%, recent efficacy rate was 73.5% and 43.4%, respectively, and there were significant statistical differences between two groups （ P 〈 0.01 ）. Conclusion The combination of PEII and TACE therapy for hypovascular liver cancer is a effective and safe medality, and it was better than using TACE only