产科围手术期抗菌药物应用分析

Analysis of antibiotics application in perioperative

目的了解我院剖宫产患者围手术期抗菌药物的应用时间与术后感染的关系。方法对我院剖宫产产妇642例,根据不同给药方案随机分为研究组128例及对照组514例,研究组为围手术期用抗生素,对照组为术后用抗生素。观察2组疗效及抗生素用量。结果研究组和对照组术后体温及退热时间、术后病率差异无统计学意义(P>0.05),研究组抗生素总量为对照组的50%～60%。结论对选择性剖宫产预防感染应用小剂量、短疗程抗生素足以达到预期效果,并以围手术期应用抗生素预防感染为宜。

Objective Understood the time of the patients with cesarean used antimierobial at perioperative and postoperative infection in our hospital. Methods According to difference dosage regimen of 642 cases of cesarean section in our hospital were divided into study group（ n = 128） and control group（n = 5] 4） randomly, study group of perJopera^Jve medication, and postoperative administration in the eontrol group. Observed the effieaey and dosage of antimicrobial. Results The body temperature,fever time and postoperative morbidity of study group and control group had no significant differenee（ P 〉0.05 ）. Total study group of antibiotics in the control group 50% - 60%. Conclusion Selective caesarean section used low-dose, short course of antibiotics suffieient to ean achieve the desired results,and used in perioperative was appropriate .