国产活检枪在甲状腺疾病活组织检查中的临床应用价值

Clinical Application of Domestic Biopsy Gun in Diagnosis of Thyroid Diseases

目的:评估国产可调式自动活检装置(活检枪)在临床甲状腺病变活组织检查中的价值。方法:使用国产第二代活检装置(活检枪)在彩超高频探头监视下,经皮穿刺对69例甲状腺疾病进行活检取材。结果:取材成功率100%,手术组88.2%(30/34)可以得出明确病理组织学诊断,对甲状腺疾病的良恶性诊断符合率(34/34)100%,无假阳性或假阴性结果。16例甲状腺疾病细针针吸细胞学诊断(FNAB)与手术病理符合率(12/16)75%,假阴性3例(将2例滤泡性腺癌误判为滤泡性腺瘤,1例将乳头状腺癌误判为滤泡性腺瘤)占(3/16)18.75%,1例恶性淋巴瘤只能作出少量异形细胞的判断,而不能作出定性诊断,占(1/16)6.25%,对1例恶性淋巴瘤只能作出少量异形细胞的判断。结论:国产可调式自动活检枪性能稳定、取材可靠,使用方便;该装置的射程可调范围广,在甲状腺等浅表组织器官病变中的活组织诊断应用中有一定优势。

Objective：To evaluate the application of Domestic biopsy gun in diagnosis of thyroid diseases.Methods：Percutaneous biopsy sample of 69 cases of thyroid diseases were collected using domestic second-generation biopsy gun with mornitoring of high-frequency color Doppler ultrasound probe.Resuits：100% of samples collection was successful.The diagnostic rate of benign and malignant thyroid disease was 100%（34/34）in the operaton group,no false positive or false negative.The diagnostic rate of pathology in operation group（n=16）in fine needle aspiration group was 75%（12/16）,and 3 of 16 cases had fasle positive（18.75%）.And one malignant lymphoma of the operation group could be determined with a small amount of special-shaped cells only,but qualitative diagnosis was not identified.Conclusions：Percutaneous use of domestic biopsy gun is safe,stable,drawing reliable,easy to use and efficacy for diagnosis of thyroid diseases.